Harvard University will reprise a $10 million investment it made 20 years in the Local Initiatives Support Corp. which, it said, helped preserve or create over 3,100 homes across 65 affordable housing developments in Boston and Cambridge.

LISC is a national investor and adviser for community development projects.

Harvard’s new investment will see $10 million directed to LISC over the next 20 years at low interest rates.

“Harvard is pleased to renew the Harvard Local Housing Collaborative. We are proud to be part of a community where partners from across Greater Boston come together to strengthen the region and address the urgent need for quality, affordable housing,” Harvard President Larry Bacow said in a statement. “We are grateful to all of our partners for their support and their efforts to increase access to homeownership and promote fair and equitable access to housing.”